2-Phenoxyethanol (Pharmaceutical Grade)CAS：122-99-6
Preservative Performance: Phenoxyethanol boasts broad-spectrum antimicrobial effects, exerting inhibitory activity against bacteria, yeasts, and molds alike. This property solidifies its position as a crucial preservative component in cosmetic and personal care products.
Safety Characteristics: With low systemic toxicity and slight irritation potential, phenoxyethanol is well-suited for both topical and injectable formulations. Its favorable dermal absorption traits further support its compatibility with such applications.
Regulatory Advantage: Frequently recognized as a preferred substitute for parabens, phenoxyethanol mitigates concerns related to possible endocrine-disrupting effects while sustaining reliable preservative functionality.
Antiseptic Function: Phenoxyethanol can effectively restrain various microbes including bacteria, fungi and moulds due to its wide-range antibacterial property. It has thus become a mainstream antiseptic ingredient commonly adopted in cosmetics and daily care goods.
Safety Features: This ingredient features low internal toxicity and mild skin irritation. It fits well in external skin products as well as injection preparations, and its moderate skin penetration also guarantees safe use in relevant formulas.
Compliance Superiority: It is widely accepted as an ideal replacement for paraben preservatives. It can avoid the hidden risk of endocrine disturbance and still keep stable and excellent antiseptic capacity.
Wide Application Fields: Apart from beauty and personal care items, it is also extensively applied in medical medicines and vaccine products. It can effectively prolong product service life and stop harmful microbial pollution.
2-Phenoxyethanol Chemical Properties
Melting point | 11-13 °C (lit.) |
Boiling point | 247 °C (lit.) |
density | 1.102 g/mL at 25 °C (lit.) |
vapor density | 4.8 (vs air) |
vapor pressure | 0.01 mm Hg ( 20 °C) |
refractive index | n20/D 1.539 |
FEMA | 4620 | 2-PHENOXYETHANOL |
Fp | >230 °F |
storage temp. | Store below +30°C. |
solubility | soluble, clear, colorless to very faintly yellow |
pka | 14.36±0.10(Predicted) |
form | Liquid |
color | Clear colorless |
Specific Gravity | 1.109 (20/4℃) |
Odor | Faint aromatic odor |
PH Range | 7 at 10 g/l at 23 °C |
PH | 7 (10g/l, H2O, 23℃) |
explosive limit | 1.4-9.0%(V) |
Odor Type | floral |
Water Solubility | 30 g/L (20 ºC) |
Merck | 14,7257 |
BRN | 1364011 |
InChIKey | QCDWFXQBSFUVSP-UHFFFAOYSA-N |
LogP | 1.2 at 23℃ |
CAS DataBase Reference | 122-99-6(CAS DataBase Reference) |
NIST Chemistry Reference | 2-Phenoxyethanol(122-99-6) |
EPA Substance Registry System | Ethylene glycol monophenyl ether (122-99-6) |
Safety Information
Hazard Codes | Xn,Xi |
Risk Statements | 22-36-R36-R22 |
Safety Statements | 26-S26 |
WGK Germany | 1 |
RTECS | KM0350000 |
Autoignition Temperature | 535 °C DIN 51794 |
Hazard Note | Irritant |
TSCA | Yes |
HS Code | 29094990 |
Hazardous Substances Data | 122-99-6(Hazardous Substances Data) |
Toxicity | LD50 orally in Rabbit: 1850 mg/kg LD50 dermal Rabbit > 2000 mg/kg |
