Calcium D-PantothenateCAS:137-08-6

Calcium Pantothenate


This natural derivative of pantothenic acid (vitamin B5) functions as an indispensable nutrient to sustain normal metabolic activities and promote general physical health.


Regulatory Compliance


It has obtained Generally Recognized as Safe (GRAS) certification in both the United States and the European Union, verifying its safety for use in food products and nutritional supplements.


Nutritional Specifications


In accordance with U.S. FDA requirements, this ingredient must be added to infant formula at a dosage of 300 μg per 100 kcal, highlighting its vital contribution to early‑stage growth and development.


Application Scope


It is extensively incorporated into dietary supplements, functional foods, and nutrient‑fortified formulations to support physical wellness throughout different age groups and life cycles.


Product Details
Calcium pantothenate, also referred to chemically as calcium D‑pantothenate, is the calcium salt of pantothenic acid (vitamin B5), a vital nutrient that exists naturally in many food materials. This ingredient is classified as Generally Recognized as Safe (GRAS) in both the United States and the European Union. According to FDA standards, commercial infant formulas are required to provide at least 300 micrograms of this key vitamin per 100 kilocalories.


Calcium D-PantothenateCAS:137-08-6


This substance is used in biochemical studies as a nutritional ingredient in cell and tissue culture media. Clinically, it is applied in the treatment of pantothenic acid insufficiency, peripheral neuritis, and post‑operative intestinal spasms.

As a nutritional fortification agent, calcium pantothenate is added to infant formula at levels ranging from 15 to 28 mg/kg. In beverage products, it is typically used at 2 to 4 mg/kg to enhance nutritional value.


Calcium D-PantothenateCAS:137-08-6


Chemical Properties & Safety Information


ItemSpecification
Melting point190 °C
Specific rotation26.5 º (c=5, H₂O)
Refractive index27 ° (C=5, H₂O)
Flash point145 °C
Storage temperature2–8 °C
SolubilityH₂O: 50 mg/mL at 25 °C, clear, nearly colorless
Physical formPowder
ColorWhite or off‑white
pH6.8–7.2 (25 °C, 50 mg/mL in H₂O)
OdorOdorless
SourceSynthetic (organic)
Optical rotation[α]20/D +27±2°, c = 5% in H₂O
Water solubilitySoluble in water
SensitivityHygroscopic
Merck14, 7015
BRN3769272
StabilityStable; sensitive to moisture or air. Incompatible with strong acids and strong bases.
InChIKeyFAPWYRCQGJNNSJ‑UBKPKTQASA‑L
LogP-0.849 (estimated)
CAS No.137‑08‑6
EPA RegistryCalcium pantothenate (137‑08‑6)
Hazard CodesXn
Risk Statements20/21/22‑37/38‑41‑48
Safety Statements24/25‑45‑36/37/39‑26‑22
WGK Germany1
RTECSRU4375000
F3‑10
TSCAListed
HS Code29362400

Calcium D-PantothenateCAS:137-08-6


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