4,4'-Diphenylmethane diisocyanate CAS：101-68-8
4,4'-Diphenylmethane diisocyanate shows strong solubility in a wide range of organic solvents, among which are acetone, benzene, kerosene and nitrobenzene.
This characteristic supports its high compatibility and wide application in many chemical production procedures. It usually appears as a light yellow molten solid, making it convenient to operate, mix and apply in different industrial production links.
Thanks to its excellent solubility and stable chemical properties, this compound is highly suitable for various uses in chemical synthesis and industrial production.
Furthermore, its volatility allows it to work effectively in scenarios requiring gas-phase reactions, including special coatings, surface modification processes and certain catalytic reactions.
4,4'-Diphenylmethane diisocyanate appears as a pale yellow molten solid with a sharp, irritating smell. It easily gives off fumes that may irritate the respiratory tract if breathed in. This substance can dissolve well in many organic solvents including acetone, benzene, kerosene and nitrobenzene, which makes it convenient for use in various chemical applications.
Nevertheless, it is only slightly soluble in water. Extra care should be taken during handling because of its high volatility and possible health hazards caused by long-term exposure to its vapors.
Parameters
| Melting point | 38-44 °C |
| Boiling point | 392 °C |
| density | 1.19 |
| vapor pressure | 0.066 hPa (20 °C) |
| refractive index | 1.5906 (estimate) |
| Fp | 196 °C |
| storage temp. | -20°C |
| solubility | 2g/l (decomposition) |
| form | solid |
| color | White to Almost white |
| Specific Gravity | 1.18 |
| explose limit | 0.4%(V) |
| Water Solubility | decomposes |
| FreezingPoint | 37℃ |
| Sensitive | Moisture Sensitive/Lachrymatory |
| BRN | 797662 |
| Exposure limits | TLV-TWA 0.051 mg/m3 (0.005 ppm) (ACGIH and NIOSH); ceiling (air) 0.204 mg/m3 (0.02 ppm)/10 min (NIOSH and OSHA); IDLH 102 mg/m3 (10 ppm). |
| Dielectric constant | 10.0（Ambient） |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. Reacts violently with alcohols. |
| CAS DataBase Reference | 101-68-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1,1'-methylenebis[4-isocyanato-(101-68-8) |
| IARC | 3 (Vol. 19, Sup 7, 71) 1999 |
| EPA Substance Registry System | 4,4'-Methylenedi(phenyl isocyanate) (101-68-8) |
Safety Information
| Hazard Codes | Xn,T,C |
| Risk Statements | 42/43-36/37/38-20-48/20-40 |
| Safety Statements | 45-36/37-23 |
| RIDADR | 2206 |
| OEB | D |
| OEL | TWA: 0.05 mg/m3 (0.005 ppm), Ceiling: 0.2 mg/m3 (0.020 ppm) [10-minute] |
| WGK Germany | 1 |
| RTECS | NQ9350000 |
| Autoignition Temperature | >600 °C |
| Hazard Note | Toxic/Corrosive/Lachrymatory/Moisture Sensitive |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | II |
| HS Code | 29291090 |
| Hazardous Substances Data | 101-68-8(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 9000 mg/kg |
| IDLA | 75 mg/m3 |
